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Gp41 dynamically interacts with the TCR in the immune synapse and promotes early T cell activation
The HIV-1 glycoprotein gp41 critically mediates CD4(+) T-cell infection by HIV-1 during viral entry, assembly, and release. Although multiple immune-regulatory activities of gp41 have been reported, the underlying mechanisms of these activities remain poorly understood. Here we employed multi-colour...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021400/ https://www.ncbi.nlm.nih.gov/pubmed/29950577 http://dx.doi.org/10.1038/s41598-018-28114-5 |