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Identification of genes associated with cortical malformation using a transposon-mediated somatic mutagenesis screen in mice
Mutations in genes involved in the production, migration, or differentiation of cortical neurons often lead to malformations of cortical development (MCDs). However, many genetic mutations involved in MCD pathogenesis remain unidentified. Here we developed a genetic screening paradigm based on trans...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021418/ https://www.ncbi.nlm.nih.gov/pubmed/29950674 http://dx.doi.org/10.1038/s41467-018-04880-8 |