Identification of genes associated with cortical malformation using a transposon-mediated somatic mutagenesis screen in mice

Mutations in genes involved in the production, migration, or differentiation of cortical neurons often lead to malformations of cortical development (MCDs). However, many genetic mutations involved in MCD pathogenesis remain unidentified. Here we developed a genetic screening paradigm based on trans...

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Detalles Bibliográficos
Autores principales: Lu, I-Ling, Chen, Chien, Tung, Chien-Yi, Chen, Hsin-Hung, Pan, Jia-Ping, Chang, Chia-Hsiang, Cheng, Jia-Shing, Chen, Yi-An, Wang, Chun-Hung, Huang, Chia-Wei, Kang, Yi-Ning, Chang, Hsin-Yun, Li, Lei-Li, Chang, Kai-Ping, Shih, Yang-Hsin, Lin, Chi-Hung, Kwan, Shang-Yeong, Tsai, Jin-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021418/
https://www.ncbi.nlm.nih.gov/pubmed/29950674
http://dx.doi.org/10.1038/s41467-018-04880-8

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