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Biomarker discovery by integrated joint non-negative matrix factorization and pathway signature analyses
Predictive biomarkers are important for selecting appropriate patients for particular treatments. Comprehensive genomic, transcriptomic, and pharmacological data provide clues for understanding relationships between biomarkers and drugs. However, it is still difficult to mine biologically meaningful...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021419/ https://www.ncbi.nlm.nih.gov/pubmed/29950679 http://dx.doi.org/10.1038/s41598-018-28066-w |