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In-vivo topical mucosal delivery of a fluorescent deoxy-glucose delineates neoplasia from normal in a preclinical model of oral epithelial neoplasia

Metabolic imaging of oral cavity mucosal surfaces could benefit early detection of oral squamous cell carcinoma (OSCC) and oral epithelial dysplasia (OED). Fluorescent deoxy-glucose agents provide contrast for glucose metabolism similar to (18)FDG-PET imaging and allow use of optical imaging, which...

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Detalles Bibliográficos
Autores principales: Pal, Rahul, Villarreal, Paula, Qiu, Suimin, Vargas, Gracie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021424/
https://www.ncbi.nlm.nih.gov/pubmed/29950704
http://dx.doi.org/10.1038/s41598-018-28014-8