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Characterizing Blood-Stage Antimalarial Drug MIC Values In Vivo Using Reinfection Patterns

The MIC is an essential quantitative measure of the asexual blood-stage effect of an antimalarial drug. In areas of high malaria transmission, and thus frequent individual infection, patients who are treated with slowly eliminated antimalarials become reinfected as drug concentrations decline. In th...

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Detalles Bibliográficos
Autores principales: Watson, James, Chu, Cindy S., Tarning, Joel, White, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021672/
https://www.ncbi.nlm.nih.gov/pubmed/29661873
http://dx.doi.org/10.1128/AAC.02476-17