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Biochemical and Functional Characterization of the Trace Amine-Associated Receptor 1 (TAAR1) Agonist RO5263397

Trace amine-associated receptor 1 (TAAR1) is a G protein-coupled receptor, which signals through elevating intracellular cAMP levels, and expressed in most vertebrates, including rodents and humans. In recent years, several lines of evidence indicated the role of TAAR1 in the regulation of dopaminer...

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Detalles Bibliográficos
Autores principales: Espinoza, Stefano, Leo, Damiana, Sotnikova, Tatyana D., Shahid, Mohammed, Kääriäinen, Tiina M., Gainetdinov, Raul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022153/
https://www.ncbi.nlm.nih.gov/pubmed/29977204
http://dx.doi.org/10.3389/fphar.2018.00645