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Identification and Characterization of a Novel Palmitoyl Acyltransferase as a Druggable Rheostat of Dynamic Palmitoylome in L. donovani

Palmitoylation has been recently identified as an important post-translational rheostat for controlling protein function in eukaryotes. However, the molecular machinery underlying palmitoylation remains unclear in the neglected tropical parasite, Leishmania donovani. Herein, we have identified a cat...

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Detalles Bibliográficos
Autores principales: Ayana, R., Yadav, Preeti, Kumari, Rajesh, Ramu, Dandugudumula, Garg, Swati, Pati, Soumya, Singh, Shailja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022219/
https://www.ncbi.nlm.nih.gov/pubmed/29977865
http://dx.doi.org/10.3389/fcimb.2018.00186