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The synthesis of water-soluble CDM-AM copolymer by irradiation and its solubilization effect on hydrophobic drugs
The β-cyclodextrin-acrylamide (CDM-AM) copolymer was prepared from acrylamide and β-CD maleate (CDM) using (60)Co γ-ray irradiation method. The optimized preparation conditions for the CDM-AM copolymer are as follows: CDM:AM mass ratio of 1:1; irradiation dose of 4 kGy; and using 20 mL of DMF water...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022224/ https://www.ncbi.nlm.nih.gov/pubmed/29962923 http://dx.doi.org/10.1080/15685551.2018.1480681 |