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Novel coumarin-6-sulfonamides as apoptotic anti-proliferative agents: synthesis, in vitro biological evaluation, and QSAR studies

Herein, we report the synthesis of different novel sets of coumarin-6-sulfonamide derivatives bearing different functionalities (4a, b, 8a–d, 11a–d, 13a, b, and 15a–c), and in vitro evaluation of their growth inhibitory activity towards the proliferation of three cancer cell lines; HepG2 (hepatocell...

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Detalles Bibliográficos
Autores principales: Sabt, Ahmed, Abdelhafez, Omaima M., El-Haggar, Radwan S., Madkour, Hassan M. F., Eldehna, Wagdy M., El-Khrisy, Ezz El-Din A. M., Abdel-Rahman, Mohamed A., Rashed, Laila. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022226/
https://www.ncbi.nlm.nih.gov/pubmed/29944015
http://dx.doi.org/10.1080/14756366.2018.1477137