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A single-cell survey of the small intestinal epithelium

Intestinal epithelial cells (IECs) absorb nutrients, respond to microbes, provide barrier function and help coordinate immune responses. We profiled 53,193 individual epithelial cells from mouse small intestine and organoids, and characterized novel subtypes and their gene signatures. We showed unex...

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Detalles Bibliográficos
Autores principales: Haber, Adam L., Biton, Moshe, Rogel, Noga, Herbst, Rebecca H., Shekhar, Karthik, Smillie, Christopher, Burgin, Grace, Delorey, Toni M., Howitt, Michael R., Katz, Yarden, Tirosh, Itay, Beyaz, Semir, Dionne, Danielle, Zhang, Mei, Raychowdhury, Raktima, Garrett, Wendy S., Rozenblatt-Rosen, Orit, Shi, Hai Ning, Yilmaz, Omer, Xavier, Ramnik J., Regev, Aviv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022292/
https://www.ncbi.nlm.nih.gov/pubmed/29144463
http://dx.doi.org/10.1038/nature24489