A Snake Venom-Secreted Phospholipase A(2) Induces Foam Cell Formation Depending on the Activation of Factors Involved in Lipid Homeostasis

MT-III, a snake venom GIIA sPLA(2), which shares structural and functional features with mammalian GIIA sPLA(2)s, activates macrophage defense functions including lipid droplet (LDs) formation, organelle involved in both lipid metabolism and inflammatory processes. Macrophages (MΦs) loaded with LDs,...

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Detalles Bibliográficos
Autores principales: Leiguez, Elbio, Giannotti, Karina Cristina, Viana, Mariana do Nascimento, Matsubara, Márcio Hideki, Fernandes, Cristina Maria, Gutiérrez, José Maria, Lomonte, Bruno, Teixeira, Catarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022332/
https://www.ncbi.nlm.nih.gov/pubmed/30013451
http://dx.doi.org/10.1155/2018/2547918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022332/
https://www.ncbi.nlm.nih.gov/pubmed/30013451
http://dx.doi.org/10.1155/2018/2547918

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