LPG: A four-group probabilistic approach to leveraging pleiotropy in genome-wide association studies

BACKGROUND: To date, genome-wide association studies (GWAS) have successfully identified tens of thousands of genetic variants among a variety of traits/diseases, shedding light on the genetic architecture of complex disease. The polygenicity of complex diseases is a widely accepted phenomenon throu...

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Detalles Bibliográficos
Autores principales: Yang, Yi, Dai, Mingwei, Huang, Jian, Lin, Xinyi, Yang, Can, Chen, Min, Liu, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022345/
https://www.ncbi.nlm.nih.gov/pubmed/29954342
http://dx.doi.org/10.1186/s12864-018-4851-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022345/
https://www.ncbi.nlm.nih.gov/pubmed/29954342
http://dx.doi.org/10.1186/s12864-018-4851-2

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