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LPG: A four-group probabilistic approach to leveraging pleiotropy in genome-wide association studies

BACKGROUND: To date, genome-wide association studies (GWAS) have successfully identified tens of thousands of genetic variants among a variety of traits/diseases, shedding light on the genetic architecture of complex disease. The polygenicity of complex diseases is a widely accepted phenomenon throu...

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Detalles Bibliográficos
Autores principales:	Yang, Yi, Dai, Mingwei, Huang, Jian, Lin, Xinyi, Yang, Can, Chen, Min, Liu, Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022345/ https://www.ncbi.nlm.nih.gov/pubmed/29954342 http://dx.doi.org/10.1186/s12864-018-4851-2

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