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The RNA surveillance proteins UPF1, UPF2 and SMG6 affect HIV-1 reactivation at a post-transcriptional level

BACKGROUND: The ability of human immunodeficiency virus type 1 (HIV-1) to form a stable viral reservoir is the major obstacle to an HIV-1 cure and post-transcriptional events contribute to the maintenance of viral latency. RNA surveillance proteins such as UPF1, UPF2 and SMG6 affect RNA stability an...

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Detalles Bibliográficos
Autores principales: Rao, Shringar, Amorim, Raquel, Niu, Meijuan, Temzi, Abdelkrim, Mouland, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022449/
https://www.ncbi.nlm.nih.gov/pubmed/29954456
http://dx.doi.org/10.1186/s12977-018-0425-2