Paternal sepsis induces alterations of the sperm methylome and dampens offspring immune responses—an animal study

BACKGROUND: Sepsis represents the utmost severe consequence of infection, involving a dysregulated and self-damaging immune response of the host. While different environmental exposures like chronic stress or malnutrition have been well described to reprogram the germline and subsequently offspring...

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Detalles Bibliográficos
Autores principales: Bomans, Katharina, Schenz, Judith, Tamulyte, Sandra, Schaack, Dominik, Weigand, Markus Alexander, Uhle, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022485/
https://www.ncbi.nlm.nih.gov/pubmed/29988283
http://dx.doi.org/10.1186/s13148-018-0522-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022485/
https://www.ncbi.nlm.nih.gov/pubmed/29988283
http://dx.doi.org/10.1186/s13148-018-0522-z

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