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Paternal sepsis induces alterations of the sperm methylome and dampens offspring immune responses—an animal study
BACKGROUND: Sepsis represents the utmost severe consequence of infection, involving a dysregulated and self-damaging immune response of the host. While different environmental exposures like chronic stress or malnutrition have been well described to reprogram the germline and subsequently offspring...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022485/ https://www.ncbi.nlm.nih.gov/pubmed/29988283 http://dx.doi.org/10.1186/s13148-018-0522-z |