NMDA receptor antagonists attenuate intrathecal morphine-induced pruritus through ERK phosphorylation

Pruritus is the most common complication of intrathecal morphine; however, its exact molecular mechanism is unclear, and treatment is challenging. The analgesic effect of N-methyl-D-aspartate (NMDA) receptor antagonists and the morphine-associated increase in NMDA receptor activation suggest potenti...

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Detalles Bibliográficos
Autores principales: Shen, Le, Wang, Weijia, Li, Siyu, Qin, Jing, Huang, Yuguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022508/
https://www.ncbi.nlm.nih.gov/pubmed/29954440
http://dx.doi.org/10.1186/s13041-018-0379-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022508/
https://www.ncbi.nlm.nih.gov/pubmed/29954440
http://dx.doi.org/10.1186/s13041-018-0379-2

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