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FFPE breast tumour blocks provide reliable sources of both germline and malignant DNA for investigation of genetic determinants of individual tumour responses to treatment

BACKGROUND: Bio-banked formalin-fixed paraffin-embedded (FFPE) tissues provide an excellent opportunity for translational genomic research. Historically matched blood has not always been collected as a source of germline DNA. This project aimed to establish if normal FFPE breast tissue could be used...

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Detalles Bibliográficos
Autores principales: Wilkins, Anna, Chauhan, Ritika, Rust, Alistair, Pearson, Alex, Daley, Frances, Manodoro, Floriana, Fenwick, Kerry, Bliss, Judith, Yarnold, John, Somaiah, Navita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022520/
https://www.ncbi.nlm.nih.gov/pubmed/29700676
http://dx.doi.org/10.1007/s10549-018-4798-7