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COSSMO: predicting competitive alternative splice site selection using deep learning

MOTIVATION: Alternative splice site selection is inherently competitive and the probability of a given splice site to be used also depends on the strength of neighboring sites. Here, we present a new model named the competitive splice site model (COSSMO), which explicitly accounts for these competit...

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Detalles Bibliográficos
Autores principales: Bretschneider, Hannes, Gandhi, Shreshth, Deshwar, Amit G, Zuberi, Khalid, Frey, Brendan J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022534/
https://www.ncbi.nlm.nih.gov/pubmed/29949959
http://dx.doi.org/10.1093/bioinformatics/bty244