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GSEA-InContext: identifying novel and common patterns in expression experiments

MOTIVATION: Gene Set Enrichment Analysis (GSEA) is routinely used to analyze and interpret coordinate pathway-level changes in transcriptomics experiments. For an experiment where less than seven samples per condition are compared, GSEA employs a competitive null hypothesis to test significance. A g...

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Detalles Bibliográficos
Autores principales: Powers, Rani K, Goodspeed, Andrew, Pielke-Lombardo, Harrison, Tan, Aik-Choon, Costello, James C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022535/
https://www.ncbi.nlm.nih.gov/pubmed/29950010
http://dx.doi.org/10.1093/bioinformatics/bty271