Strand-seq enables reliable separation of long reads by chromosome via expectation maximization

MOTIVATION: Current sequencing technologies are able to produce reads orders of magnitude longer than ever possible before. Such long reads have sparked a new interest in de novo genome assembly, which removes reference biases inherent to re-sequencing approaches and allows for a direct characteriza...

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Detalles Bibliográficos
Autores principales: Ghareghani, Maryam, Porubskỳ, David, Sanders, Ashley D, Meiers, Sascha, Eichler, Evan E, Korbel, Jan O, Marschall, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Ismb 2018–Intelligent Systems for Molecular Biology Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022540/
https://www.ncbi.nlm.nih.gov/pubmed/29949971
http://dx.doi.org/10.1093/bioinformatics/bty290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022540/
https://www.ncbi.nlm.nih.gov/pubmed/29949971
http://dx.doi.org/10.1093/bioinformatics/bty290

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