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Strand-seq enables reliable separation of long reads by chromosome via expectation maximization
MOTIVATION: Current sequencing technologies are able to produce reads orders of magnitude longer than ever possible before. Such long reads have sparked a new interest in de novo genome assembly, which removes reference biases inherent to re-sequencing approaches and allows for a direct characteriza...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022540/ https://www.ncbi.nlm.nih.gov/pubmed/29949971 http://dx.doi.org/10.1093/bioinformatics/bty290 |