pBRIT: gene prioritization by correlating functional and phenotypic annotations through integrative data fusion

MOTIVATION: Computational gene prioritization can aid in disease gene identification. Here, we propose pBRIT (prioritization using Bayesian Ridge regression and Information Theoretic model), a novel adaptive and scalable prioritization tool, integrating Pubmed abstracts, Gene Ontology, Sequence simi...

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Detalles Bibliográficos
Autores principales: Kumar, Ajay Anand, Van Laer, Lut, Alaerts, Maaike, Ardeshirdavani, Amin, Moreau, Yves, Laukens, Kris, Loeys, Bart, Vandeweyer, Geert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022555/
https://www.ncbi.nlm.nih.gov/pubmed/29452392
http://dx.doi.org/10.1093/bioinformatics/bty079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022555/
https://www.ncbi.nlm.nih.gov/pubmed/29452392
http://dx.doi.org/10.1093/bioinformatics/bty079

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