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Classifying tumors by supervised network propagation

MOTIVATION: Network propagation has been widely used to aggregate and amplify the effects of tumor mutations using knowledge of molecular interaction networks. However, propagating mutations through interactions irrelevant to cancer leads to erosion of pathway signals and complicates the identificat...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Ma, Jianzhu, Ideker, Trey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022559/
https://www.ncbi.nlm.nih.gov/pubmed/29949979
http://dx.doi.org/10.1093/bioinformatics/bty247