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Accurate prediction of orthologs in the presence of divergence after duplication

MOTIVATION: When gene duplication occurs, one of the copies may become free of selective pressure and evolve at an accelerated pace. This has important consequences on the prediction of orthology relationships, since two orthologous genes separated by divergence after duplication may differ in both...

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Detalles Bibliográficos
Autores principales: Lafond, Manuel, Meghdari Miardan, Mona, Sankoff, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022570/
https://www.ncbi.nlm.nih.gov/pubmed/29950018
http://dx.doi.org/10.1093/bioinformatics/bty242