Haplotype phasing in single-cell DNA-sequencing data

MOTIVATION: Current technologies for single-cell DNA sequencing require whole-genome amplification (WGA), as a single cell contains too little DNA for direct sequencing. Unfortunately, WGA introduces biases in the resulting sequencing data, including non-uniformity in genome coverage and high rates...

Descripción completa

Detalles Bibliográficos
Autores principales: Satas, Gryte, Raphael, Benjamin J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Ismb 2018–Intelligent Systems for Molecular Biology Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022575/
https://www.ncbi.nlm.nih.gov/pubmed/29950014
http://dx.doi.org/10.1093/bioinformatics/bty286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022575/
https://www.ncbi.nlm.nih.gov/pubmed/29950014
http://dx.doi.org/10.1093/bioinformatics/bty286

Ejemplares similares