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Haplotype phasing in single-cell DNA-sequencing data
MOTIVATION: Current technologies for single-cell DNA sequencing require whole-genome amplification (WGA), as a single cell contains too little DNA for direct sequencing. Unfortunately, WGA introduces biases in the resulting sequencing data, including non-uniformity in genome coverage and high rates...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022575/ https://www.ncbi.nlm.nih.gov/pubmed/29950014 http://dx.doi.org/10.1093/bioinformatics/bty286 |