A spectral clustering-based method for identifying clones from high-throughput B cell repertoire sequencing data

MOTIVATION: B cells derive their antigen-specificity through the expression of Immunoglobulin (Ig) receptors on their surface. These receptors are initially generated stochastically by somatic re-arrangement of the DNA and further diversified following antigen-activation by a process of somatic hype...

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Detalles Bibliográficos
Autores principales: Nouri, Nima, Kleinstein, Steven H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Ismb 2018–Intelligent Systems for Molecular Biology Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022594/
https://www.ncbi.nlm.nih.gov/pubmed/29949968
http://dx.doi.org/10.1093/bioinformatics/bty235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022594/
https://www.ncbi.nlm.nih.gov/pubmed/29949968
http://dx.doi.org/10.1093/bioinformatics/bty235

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