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A spectral clustering-based method for identifying clones from high-throughput B cell repertoire sequencing data
MOTIVATION: B cells derive their antigen-specificity through the expression of Immunoglobulin (Ig) receptors on their surface. These receptors are initially generated stochastically by somatic re-arrangement of the DNA and further diversified following antigen-activation by a process of somatic hype...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022594/ https://www.ncbi.nlm.nih.gov/pubmed/29949968 http://dx.doi.org/10.1093/bioinformatics/bty235 |