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Personalized regression enables sample-specific pan-cancer analysis

MOTIVATION: In many applications, inter-sample heterogeneity is crucial to understanding the complex biological processes under study. For example, in genomic analysis of cancers, each patient in a cohort may have a different driver mutation, making it difficult or impossible to identify causal muta...

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Detalles Bibliográficos
Autores principales: Lengerich, Benjamin J, Aragam, Bryon, Xing, Eric P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022603/
https://www.ncbi.nlm.nih.gov/pubmed/29949997
http://dx.doi.org/10.1093/bioinformatics/bty250