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Insulin signalling promotes dendrite and synapse regeneration and restores circuit function after axonal injury
Dendrite pathology and synapse disassembly are critical features of chronic neurodegenerative diseases. In spite of this, the capacity of injured neurons to regenerate dendrites has been largely ignored. Here, we show that, upon axonal injury, retinal ganglion cells undergo rapid dendritic retractio...
Autores principales: | Agostinone, Jessica, Alarcon-Martinez, Luis, Gamlin, Clare, Yu, Wan-Qing, Wong, Rachel O L, Di Polo, Adriana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022605/ https://www.ncbi.nlm.nih.gov/pubmed/29931057 http://dx.doi.org/10.1093/brain/awy142 |
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