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An evolutionary model motivated by physicochemical properties of amino acids reveals variation among proteins
MOTIVATION: The relative rates of amino acid interchanges over evolutionary time are likely to vary among proteins. Variation in those rates has the potential to reveal information about constraints on proteins. However, the most straightforward model that could be used to estimate relative rates of...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Oxford University Press
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022633/ https://www.ncbi.nlm.nih.gov/pubmed/29950007 http://dx.doi.org/10.1093/bioinformatics/bty261 |