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An evolutionary model motivated by physicochemical properties of amino acids reveals variation among proteins

MOTIVATION: The relative rates of amino acid interchanges over evolutionary time are likely to vary among proteins. Variation in those rates has the potential to reveal information about constraints on proteins. However, the most straightforward model that could be used to estimate relative rates of...

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Detalles Bibliográficos
Autor principal: Braun, Edward L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022633/
https://www.ncbi.nlm.nih.gov/pubmed/29950007
http://dx.doi.org/10.1093/bioinformatics/bty261