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SubRecon: ancestral reconstruction of amino acid substitutions along a branch in a phylogeny

SUMMARY: Existing ancestral sequence reconstruction techniques are ill-suited to investigating substitutions on a single branch of interest. We present SubRecon, an implementation of a hybrid technique integrating joint and marginal reconstruction for protein sequence data. SubRecon calculates the j...

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Detalles Bibliográficos
Autores principales: Monit, Christopher, Goldstein, Richard A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022634/
https://www.ncbi.nlm.nih.gov/pubmed/29506148
http://dx.doi.org/10.1093/bioinformatics/bty101