Cargando…
Viral quasispecies reconstruction via tensor factorization with successive read removal
MOTIVATION: As RNA viruses mutate and adapt to environmental changes, often developing resistance to anti-viral vaccines and drugs, they form an ensemble of viral strains––a viral quasispecies. While high-throughput sequencing (HTS) has enabled in-depth studies of viral quasispecies, sequencing erro...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022648/ https://www.ncbi.nlm.nih.gov/pubmed/29949976 http://dx.doi.org/10.1093/bioinformatics/bty291 |