Novo&Stitch: accurate reconciliation of genome assemblies via optical maps

MOTIVATION: De novo genome assembly is a challenging computational problem due to the high repetitive content of eukaryotic genomes and the imperfections of sequencing technologies (i.e. sequencing errors, uneven sequencing coverage and chimeric reads). Several assembly tools are currently available...

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Detalles Bibliográficos
Autores principales: Pan, Weihua, Wanamaker, Steve I, Ah-Fong, Audrey M V, Judelson, Howard S, Lonardi, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Ismb 2018–Intelligent Systems for Molecular Biology Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022655/
https://www.ncbi.nlm.nih.gov/pubmed/29949964
http://dx.doi.org/10.1093/bioinformatics/bty255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022655/
https://www.ncbi.nlm.nih.gov/pubmed/29949964
http://dx.doi.org/10.1093/bioinformatics/bty255

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