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Novo&Stitch: accurate reconciliation of genome assemblies via optical maps
MOTIVATION: De novo genome assembly is a challenging computational problem due to the high repetitive content of eukaryotic genomes and the imperfections of sequencing technologies (i.e. sequencing errors, uneven sequencing coverage and chimeric reads). Several assembly tools are currently available...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022655/ https://www.ncbi.nlm.nih.gov/pubmed/29949964 http://dx.doi.org/10.1093/bioinformatics/bty255 |