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ShinyKGode: an interactive application for ODE parameter inference using gradient matching

MOTIVATION: Mathematical modelling based on ordinary differential equations (ODEs) is widely used to describe the dynamics of biological systems, particularly in systems and pathway biology. Often the kinetic parameters of these ODE systems are unknown and have to be inferred from the data. Approxim...

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Detalles Bibliográficos
Autores principales: Wandy, Joe, Niu, Mu, Giurghita, Diana, Daly, Rónán, Rogers, Simon, Husmeier, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022662/
https://www.ncbi.nlm.nih.gov/pubmed/29490021
http://dx.doi.org/10.1093/bioinformatics/bty089