Driver gene mutations based clustering of tumors: methods and applications

MOTIVATION: Somatic mutations in proto-oncogenes and tumor suppressor genes constitute a major category of causal genetic abnormalities in tumor cells. The mutation spectra of thousands of tumors have been generated by The Cancer Genome Atlas (TCGA) and other whole genome (exome) sequencing projects...

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Detalles Bibliográficos
Autores principales: Zhang, Wensheng, Flemington, Erik K, Zhang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Ismb 2018–Intelligent Systems for Molecular Biology Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022677/
https://www.ncbi.nlm.nih.gov/pubmed/29950003
http://dx.doi.org/10.1093/bioinformatics/bty232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022677/
https://www.ncbi.nlm.nih.gov/pubmed/29950003
http://dx.doi.org/10.1093/bioinformatics/bty232

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