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Improving genomics-based predictions for precision medicine through active elicitation of expert knowledge

MOTIVATION: Precision medicine requires the ability to predict the efficacies of different treatments for a given individual using high-dimensional genomic measurements. However, identifying predictive features remains a challenge when the sample size is small. Incorporating expert knowledge offers...

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Detalles Bibliográficos
Autores principales: Sundin, Iiris, Peltola, Tomi, Micallef, Luana, Afrabandpey, Homayun, Soare, Marta, Mamun Majumder, Muntasir, Daee, Pedram, He, Chen, Serim, Baris, Havulinna, Aki, Heckman, Caroline, Jacucci, Giulio, Marttinen, Pekka, Kaski, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022689/
https://www.ncbi.nlm.nih.gov/pubmed/29949984
http://dx.doi.org/10.1093/bioinformatics/bty257