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Improving genomics-based predictions for precision medicine through active elicitation of expert knowledge
MOTIVATION: Precision medicine requires the ability to predict the efficacies of different treatments for a given individual using high-dimensional genomic measurements. However, identifying predictive features remains a challenge when the sample size is small. Incorporating expert knowledge offers...
Autores principales: | Sundin, Iiris, Peltola, Tomi, Micallef, Luana, Afrabandpey, Homayun, Soare, Marta, Mamun Majumder, Muntasir, Daee, Pedram, He, Chen, Serim, Baris, Havulinna, Aki, Heckman, Caroline, Jacucci, Giulio, Marttinen, Pekka, Kaski, Samuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022689/ https://www.ncbi.nlm.nih.gov/pubmed/29949984 http://dx.doi.org/10.1093/bioinformatics/bty257 |
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