AmpUMI: design and analysis of unique molecular identifiers for deep amplicon sequencing

MOTIVATION: Unique molecular identifiers (UMIs) are added to DNA fragments before PCR amplification to discriminate between alleles arising from the same genomic locus and sequencing reads produced by PCR amplification. While computational methods have been developed to take into account UMI informa...

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Detalles Bibliográficos
Autores principales: Clement, Kendell, Farouni, Rick, Bauer, Daniel E, Pinello, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Ismb 2018–Intelligent Systems for Molecular Biology Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022702/
https://www.ncbi.nlm.nih.gov/pubmed/29949956
http://dx.doi.org/10.1093/bioinformatics/bty264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022702/
https://www.ncbi.nlm.nih.gov/pubmed/29949956
http://dx.doi.org/10.1093/bioinformatics/bty264

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