A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers

BACKGROUND: Precision medicine therapies require identification of unique molecular cancer characteristics. Hexokinase (HK) activity has been proposed as a therapeutic target; however, different hexokinase isoforms have not been well characterized as alternative targets. While HK2 is highly expresse...

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Detalles Bibliográficos
Autores principales: Xu, Shili, Catapang, Arthur, Braas, Daniel, Stiles, Linsey, Doh, Hanna M., Lee, Jason T., Graeber, Thomas G., Damoiseaux, Robert, Shirihai, Orian, Herschman, Harvey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022704/
https://www.ncbi.nlm.nih.gov/pubmed/29988332
http://dx.doi.org/10.1186/s40170-018-0181-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022704/
https://www.ncbi.nlm.nih.gov/pubmed/29988332
http://dx.doi.org/10.1186/s40170-018-0181-8

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