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A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers
BACKGROUND: Precision medicine therapies require identification of unique molecular cancer characteristics. Hexokinase (HK) activity has been proposed as a therapeutic target; however, different hexokinase isoforms have not been well characterized as alternative targets. While HK2 is highly expresse...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022704/ https://www.ncbi.nlm.nih.gov/pubmed/29988332 http://dx.doi.org/10.1186/s40170-018-0181-8 |