Modeling polypharmacy side effects with graph convolutional networks

MOTIVATION: The use of drug combinations, termed polypharmacy, is common to treat patients with complex diseases or co-existing conditions. However, a major consequence of polypharmacy is a much higher risk of adverse side effects for the patient. Polypharmacy side effects emerge because of drug–dru...

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Detalles Bibliográficos
Autores principales: Zitnik, Marinka, Agrawal, Monica, Leskovec, Jure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Ismb 2018–Intelligent Systems for Molecular Biology Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022705/
https://www.ncbi.nlm.nih.gov/pubmed/29949996
http://dx.doi.org/10.1093/bioinformatics/bty294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022705/
https://www.ncbi.nlm.nih.gov/pubmed/29949996
http://dx.doi.org/10.1093/bioinformatics/bty294

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