Benzimidazoisoquinoline derivatives inhibit glioblastoma cell proliferation through down-regulating Raf/MEK/ERK and PI3K/AKT pathways

BACKGROUND: Recent studies showed that benzimidazoleisoquinolinone derivatives exhibit anticancer activity against human cancer cell lines. The aim of this study is to evaluate the anti-tumor effects and mechanisms of benzimidazoleisoquinolinones in isocitrate dehydrogenase-wildtype subtype of human...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Ya-Jun, Xu, Zhi-Gang, Li, Shi-Qiang, He, Liu-Jun, Tang, Yan, Chen, Zhong-Zhu, Yang, Dong-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022716/
https://www.ncbi.nlm.nih.gov/pubmed/29988358
http://dx.doi.org/10.1186/s12935-018-0588-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022716/
https://www.ncbi.nlm.nih.gov/pubmed/29988358
http://dx.doi.org/10.1186/s12935-018-0588-x

Ejemplares similares