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Open Conformation of the Escherichia coli Periplasmic Murein Tripeptide Binding Protein, MppA, at High Resolution

Periplasmic ligand-binding proteins (PBPs) bind ligands with a high affinity and specificity. They undergo a large conformational change upon ligand binding, and they have a robust protein fold. These physical features have made them ideal candidates for use in protein engineering projects to develo...

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Detalles Bibliográficos
Autores principales: Bhatt, Forum, Patel, Vishal, Jeffery, Constance J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022919/
https://www.ncbi.nlm.nih.gov/pubmed/29783769
http://dx.doi.org/10.3390/biology7020030