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Our Evolving Understanding of the Mechanism of Quinolones

The maintenance of DNA supercoiling is essential for the proper regulation of a plethora of biological processes. As a consequence of this mode of regulation, ahead of the replication fork, DNA replication machinery is prone to introducing supercoiled regions into the DNA double helix. Resolution of...

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Detalles Bibliográficos
Autores principales: Gutierrez, Arnaud, Stokes, Jonathan M., Matic, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023003/
https://www.ncbi.nlm.nih.gov/pubmed/29642475
http://dx.doi.org/10.3390/antibiotics7020032