Redesigning TOR Kinase to Explore the Structural Basis for TORC1 and TORC2 Assembly

TOR is a serine/threonine protein kinase that assembles into distinct TOR Complexes 1 and 2 (TORC1 or TORC2) to regulate cell growth. In mammalian cells, a single mTOR incorporates stably into mTORC1 and mTORC2. By contrast, in Saccharomyces cerevisiae, two highly similar Tor1 and Tor2 proteins exis...

Descripción completa

Detalles Bibliográficos
Autores principales: Hill, Andrew, Niles, Brad, Cuyegkeng, Andrew, Powers, Ted
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023025/
https://www.ncbi.nlm.nih.gov/pubmed/29865216
http://dx.doi.org/10.3390/biom8020036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023025/
https://www.ncbi.nlm.nih.gov/pubmed/29865216
http://dx.doi.org/10.3390/biom8020036

Ejemplares similares