Pharmaceutical Machine Learning: Virtual High-Throughput Screens Identifying Promising and Economical Small Molecule Inhibitors of Complement Factor C1s

When excessively activated, C1 is insufficiently regulated, which results in tissue damage. Such tissue damage causes the complement system to become further activated to remove the resulting tissue damage, and a vicious cycle of activation/tissue damage occurs. Current Food and Drug Administration...

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Detalles Bibliográficos
Autores principales: Chen, Jonathan J., Schmucker, Lyndsey N., Visco, Donald P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023033/
https://www.ncbi.nlm.nih.gov/pubmed/29735903
http://dx.doi.org/10.3390/biom8020024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023033/
https://www.ncbi.nlm.nih.gov/pubmed/29735903
http://dx.doi.org/10.3390/biom8020024

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